Association between-514C -> T polymorphism of the hepatic lipase gene and coronary artery disease in a Turkish population

Guendogdu F., Gurlertop Y., Pirim I., Aksakal E., DOĞAN H., İSLAMOĞLU Y., ...Daha Fazla

ACTA CARDIOLOGICA, cilt.63, sa.2, ss.197-202, 2008 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 63 Sayı: 2
  • Basım Tarihi: 2008
  • Doi Numarası: 10.2143/ac.63.2.2029528
  • Dergi Adı: ACTA CARDIOLOGICA
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.197-202
  • Atatürk Üniversitesi Adresli: Evet

Özet

Objective - The main function of hepatic lipase (HL) with respect to high-density lipoprotein (HDL) is hydrolysis of phospholipids and triglycerides. The -514C -> T polymorphism in the promoter region of the hepatic lipase gene affects HL activity. We aimed to investigate the association between the frequency of the -514C -> T polymorphism of hepatic lipase (PHL) and CAD in the East Anatolian region of Turkey.