Effect of mutation in active site residue Trp209 to Val, Leu, Ile and Pro on the catalytic activity and affinity for some benzenesulfonamides of human carbonic anhydrase II

Kılıç D., Erdoğan O., Küfrevioğlu Ö. İ.

Turkish Journal of Biology, cilt.41, ss.835-842, 2017 (SCI-Expanded) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 41
  • Basım Tarihi: 2017
  • Doi Numarası: 10.3906/biy-1705-37
  • Dergi Adı: Turkish Journal of Biology
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, TR DİZİN (ULAKBİM)
  • Sayfa Sayıları: ss.835-842
  • Anahtar Kelimeler: Computational mutagenesis, enzyme inhibitor, human carbonic anhydrase II, site-directed mutagenesis, sulfonamide, AMINO-ACID SUBSTITUTIONS, HYDROPHOBIC POCKET, INHIBITORS, CONSEQUENCES, MUTANTS
  • Atatürk Üniversitesi Adresli: Evet