INVESTIGATION OF COMPLETE BLOOD COUNT INDICES (NLR, LMR, PLR, MPV/PLT, SIRI, and SII) LEVELS IN DOGS WITH PARVOVIRAL ENTERITIS COMPLICATED BY SYSTEMIC INFLAMMATORY RESPONSE SYNDROME


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Aydın Ö.

9th International Congress on Advances in Veterinary Sciences & Technics (ICABB), Aksaray, Türkiye, 23 - 27 Eylül 2024, ss.47-57

  • Yayın Türü: Bildiri / Tam Metin Bildiri
  • Basıldığı Şehir: Aksaray
  • Basıldığı Ülke: Türkiye
  • Sayfa Sayıları: ss.47-57
  • Atatürk Üniversitesi Adresli: Evet

Özet

It is believed that canine parvovirus type 2 evolved either as a result of the

differentiation of the feline panleukopenia virus or from a mutation of another wildlife

virus type. Complete blood count is an inexpensive and straightforward method used

in both human and veterinary medicine for disease confirmation and for determining

the number and relationships of blood cells such as neutrophils, lymphocytes, and

platelets. While the neutrophil-to-lymphocyte ratio (NLR), lymphocyte-to-monocyte

ratio (LMR), platelet-to-lymphocyte ratio (PLR), mean platelet volume-to-platelet ratio

(MPV/PLT), systemic immune-inflammation index (SII), and systemic inflammatory

response index (SIRI) are frequently used for confirming inflammatory diseases in

human medicine, these markers have only recently begun to be utilized in veterinary

medicine. This study focuses on investigating these markers in dogs with parvoviral

enteritis that are showing symptoms of systemic inflammatory response syndrome

(SIRS). The study consists of two groups: a control group (22 healthy dogs of different

breeds) and a patient group (60 dogs of different breeds). It was found that the values

of WBC, NEU, NLR, SIRI, and SII were higher in the patient group compared to the

control group. There was no significant difference between the groups in other

haematological parameters. In conclusion, it was determined that hematologic indices

yield significant results in dogs with parvoviral enteritis complicated by SIRS, and that

these indices are valuable for validating inflammatory conditions associated with

parvoviral enteritis.