Akademik Veri Yönetim Sistemi
PHYTOPHARMACOLOGY AND THERAPEUTIC VALUES V, cilt.23, ss.157-170, 2009 (Hakemli Dergi)
People have more interest in cowslip (Primula veris) in recent years as it has different areas to be applied especialy within the food, pharmacology and cosmetic world. This study aimed at evaluating the in vitro antioxidant activity of water and ethanol extracts of cowslip (Primula veris). In the present study, the antioxidant properties of the cowslip were evaluated by using different in vitro antioxidant assays such as 2-azino-bis(3-ethylbenzthiazoline-6-sulfonic acid) (ABTS) radical scavenging, 1,1-diphenyl-2-picryl-hydrazyl free radical (DPPH center dot) scavenging, total antioxidant activity by ferric thiocyanate method, total reductive capability using the potassium ferricyanide reduction method, superoxide anion radical scavenging and metal chelating activities. alpha-Tocopherol, butylated hydroxyanisole (BHA), and butylated hydroxytoluene (BHT) were used as the reference antioxidant compounds. The concentrations of 10, 30, and 50 mu g/mL of water and ethanol extracts of cowslip showed 96.6, 97.0, 98.2, 87.3, 91.6, 96.3% inhibition on peroxidation of linoleic acid emulsion, respectively. On the other hand, 30 mu g/ml of standard antioxidant such as a-tocopherol indicated an inhibition of 87.3% on peroxidation of linoleic acid emulsion. In addition cowslip is an effective ABTS(center dot+) scavenging, DPPH center dot scavenging, superoxide anion radical scavenging, total reducing power and metal chelating on ferrous ions activities.