Study of drug loadings on nanoparticles
National Conference on Undergraduate Research (NCUR 2011) , Utah, Amerika Birleşik Devletleri, 31 Mart - 02 Nisan 2011, ss.21-22, (Özet Bildiri)
- Yayın Türü: Bildiri / Özet Bildiri
- Basıldığı Şehir: Utah
- Basıldığı Ülke: Amerika Birleşik Devletleri
- Sayfa Sayıları: ss.21-22
- Atatürk Üniversitesi Adresli: Hayır
Özet
Superparamagnetic iron oxide nanoparticles (SPIONS) and model silica nanoparticles have been functionalised using amino silane and used in in vitro study of loading and releasing of an anticancer drug (Mitomycin C) by two different methods of surface functionalisation i.e. (i)Tri-phasic reverse emulsion (TPRE) using toluene as a solvent and (ii) in water. Finally, the loading (100C) and releasing ability (370C) of Mitomycin C was determined by UV-Visible spectrophotometer.