G20210A prothrombin gene variant in Turkish patients with angiographically documented coronary artery disease

GÜNDOĞDU, Fuat; Gurlertop, Yekta; Pirim, Ibrahim; Arslan, Sakir; Ikbal, Mevlut; Islamoglu, Yahya; Aksoy, Hülya; Senocak, Hüseyin; ŞENOCAK, Hüseyin

doi:10.1007/s11239-007-0019-7

G20210A prothrombin gene variant in Turkish patients with angiographically documented coronary artery disease

GÜNDOĞDU F., Gurlertop Y., Pirim I., Arslan S., Ikbal M., Islamoglu Y., ...Daha Fazla

JOURNAL OF THROMBOSIS AND THROMBOLYSIS, cilt.24, sa.3, ss.255-259, 2007 (SCI-Expanded, Scopus)

Yayın Türü: Makale / Tam Makale
Cilt numarası: 24 Sayı: 3
Basım Tarihi: 2007
Doi Numarası: 10.1007/s11239-007-0019-7
Dergi Adı: JOURNAL OF THROMBOSIS AND THROMBOLYSIS
Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Sayfa Sayıları: ss.255-259
Atatürk Üniversitesi Adresli: Evet

Özet

Background G -> A substitution at position 20210A in the 3'-untranslated region in prothrombin gene is associated with raised plasma prothrombin. G20210A prothrombin variant has been associated with high prothrombin levels and an increased risk of venous thrombosis. To determine the prevalence of the G20210A prothrombin variant among Turkish and to evaluate the potential relevance of this variant to Turkish patients with angiographically documented coronary artery disease (CAD).