A Ritter-Type Route to Diarylmethane Amides from <i>para</i>-Quinone Methides

Akyildiz V., SARAÇOĞLU N.

ASIAN JOURNAL OF ORGANIC CHEMISTRY, cilt.12, sa.6, 2023 (SCI-Expanded) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 12 Sayı: 6
  • Basım Tarihi: 2023
  • Doi Numarası: 10.1002/ajoc.202300121
  • Dergi Adı: ASIAN JOURNAL OF ORGANIC CHEMISTRY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Applied Science & Technology Source, Chemical Abstracts Core, Index Chemicus (IC), Current Chemical Reactions (CCR)
  • Anahtar Kelimeler: benzhydryl amides, 1, 6-conjugate addition, heterogeneous catalysis, para-quinone methide, Ritter type amidation, 1,6-ADDITION
  • Atatürk Üniversitesi Adresli: Evet

Özet

1,6-Conjugate addition/Ritter-type amidation of para-quinone methides (p-QMs) with nitriles is described. This transformation is an environmentally friendly approach by the use of NaHSO4 as a low-loading, inexpensive, green, and recyclable catalyst. Diarylmethane amides are afforded in excellent yields through a one-pot process from p-QMs and nitrile derivatives under mild reaction conditions.