Green synthesis of pyrazole systems under solvent-free conditions

SOLTANZADEH Z., IMANZADEH G., NOROOZİ-PESYAN N., ŞAHİN E.

GREEN CHEMISTRY LETTERS AND REVIEWS, cilt.10, sa.3, ss.148-153, 2017 (SCI-Expanded) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 10 Sayı: 3
  • Basım Tarihi: 2017
  • Doi Numarası: 10.1080/17518253.2017.1330428
  • Dergi Adı: GREEN CHEMISTRY LETTERS AND REVIEWS
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.148-153
  • Anahtar Kelimeler: Pyrazole systems, 1,2-dibenzoylhydrazines, green method, solvent-free conditions, tetrabutylammonium bromide, CYCLIC HYDRAZINE DERIVATIVES, BIOLOGICAL EVALUATION, DIALKYL ACETYLENEDICARBOXYLATES, HETEROCYCLIC-COMPOUNDS, MICHAEL ADDITION, ISOCYANIDES, DESIGN
  • Atatürk Üniversitesi Adresli: Evet

Özet

In this paper, we offered a green, environment-friendly, novel and inexpensive method for the synthesis of a series of pyrazole derivatives. The reaction took place in the presence of tetrabutylammonium bromide, a commercially available organic ionic salt, at room temperature under solvent-free conditions. All products were confirmed by infrared radiation, nuclear magnetic resonance and elemental analysis. Yields of products were 75-86%.