Synthesis, characterization, and photophysical properties of paraben substituted cyclotriphosphazenes with hydrophilic side groups

Senkuytu E., Eserci H., Bayik N., Akbas N., Okutan E., Ciftci G. Y.

PHOSPHORUS SULFUR AND SILICON AND THE RELATED ELEMENTS, cilt.195, sa.7, ss.570-579, 2020 (SCI-Expanded) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 195 Sayı: 7
  • Basım Tarihi: 2020
  • Doi Numarası: 10.1080/10426507.2020.1728759
  • Dergi Adı: PHOSPHORUS SULFUR AND SILICON AND THE RELATED ELEMENTS
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier
  • Sayfa Sayıları: ss.570-579
  • Anahtar Kelimeler: Paraben, cyclotriphosphazene, hydrophilic tails, UV-vis absorption, fluorescence, DNA INTERACTION ANALYSIS, CYCLOPHOSPHAZENES, DEGRADATION, DENDRIMERS
  • Atatürk Üniversitesi Adresli: Evet

Özet

In this study, five new paraben substituted cyclotriphosphazene compounds containing hydrophilic glycol groups were successfully synthesized. All synthesized cyclotriphosphazene compounds 1-10 were fully characterized via general spectroscopic techniques such as H-1, P-31 NMR and MALDI-TOF mass spectrometry. In addition, the investigations of the UV-vis absorption and fluorescence emission properties of the 1-10 carried out via absorption and fluorescence spectroscopies in different solvents. The absorbance bands of the all synthesized compounds 1-10 were observed at about 230-300 nm in all solvents studied. Furthermore, the highest fluorescence emission intensity of the compounds 1-10 was observed in tetrahydrofuran at about 312 nm and the lowest emission intensity was observed in chloroform. The synthesized molecules can be used as custom designed molecules to investigate the DNA binding properties in automatic biosensor device in our laboratories, since they carry hydrophilic glycol units for water solubility and paraben derivatives for DNA effecting properties.