INVESTIGATION OF INHIBITORY EFFECT OF HUMIC ACID ON ACETYLCHOLINESTERASE AND BUTYRYLCHOLINESTERASE ENZYMES

Akincioglu H., GÜLÇİN İ., ALWASEL S. H.

FRESENIUS ENVIRONMENTAL BULLETIN, cilt.26, sa.6, ss.3733-3739, 2017 (SCI-Expanded) identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 26 Sayı: 6
  • Basım Tarihi: 2017
  • Dergi Adı: FRESENIUS ENVIRONMENTAL BULLETIN
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED)
  • Sayfa Sayıları: ss.3733-3739
  • Anahtar Kelimeler: Humic acid, Acetylcholinesterase, Butyrylcholinesterase, Enzyme inhibition, Acetylcholine, Butrylcholine, CARBONIC-ANHYDRASE ISOENZYMES, GLUTATHIONE-S-TRANSFERASE, ALZHEIMERS-DISEASE, BIOLOGICAL EVALUATION, ESTERASE INHIBITORS, HCA I, DERIVATIVES, XII, ANTIOXIDANT, LACTOPEROXIDASE
  • Atatürk Üniversitesi Adresli: Evet

Özet

Humic acid is a principal component of humic substances, which is the major organic constituents of soil, coal, peat, many upland streams, dystrophic lakes, and ocean water. It is produced by the biodegradation of dead organic matters. Humic substances contain major groups for chemistry, such as polyphenols, polycarboxylic acids, carbonyl groups, and peroxides. The presence of carboxylate and phenolate groups gives the humic acids the ability to form complexes with ions such as, Fe2+, Fe3+, Mg2+, and Ca2+.