The prognostic significance of hemoglobin-to-red cell distribution width ratio in muscle-invasive bladder cancer

YILMAZ A., Yilmaz H., TEKİN S. B., BİLİCİ M.

BIOMARKERS IN MEDICINE, cilt.14, sa.9, ss.727-738, 2020 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 14 Sayı: 9
  • Basım Tarihi: 2020
  • Doi Numarası: 10.2217/bmm-2020-0045
  • Dergi Adı: BIOMARKERS IN MEDICINE
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, BIOSIS, Chemical Abstracts Core, EMBASE, MEDLINE
  • Sayfa Sayıları: ss.727-738
  • Atatürk Üniversitesi Adresli: Evet

Özet

Aim:To investigate the prognostic significance of pretreatment hemoglobin (HB)-to-red cell distribution width (RDW) ratio (HRR) in patients with muscle-invasive bladder cancer (MIBC).Materials & methods:The neutrophil-to-lymphocyte ratio (NLR), systemic immune-inflammation index (SII), prognostic nutritional index, HRR, HB and RDW were analyzed to assess their prognostic value using the Kaplan-Meier curves and Cox-regression analysis in 152 patients with MIBC.Results:Univariate analysis showed that the progression-free survival (PFS) was associated with NLR, SII, HRR, RDW, whereas overall survival (OS) was associated with NLR, SII, prognostic nutritional index, HRR, HB, RDW. In multivariate analysis, HRR was found to be an independent prognostic factor for both PFS and OS.Conclusion:HRR is a new prognostic factor that can be used to predict PFS/OS in MIBC.