Evaluation of alpha defensin, IL-1 receptor antagonist, and IL-18 levels in COVID-19 patients with macrophage activation syndrome and acute respiratory distress syndrome.

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Kerget B., Kerget F., Aksakal A., Aşkın S., Sağlam L., Akgün M.

Journal of medical virology, cilt.93, sa.4, ss.2090-2098, 2021 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 93 Sayı: 4
  • Basım Tarihi: 2021
  • Doi Numarası: 10.1002/jmv.26589
  • Dergi Adı: Journal of medical virology
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, BIOSIS, CAB Abstracts, EMBASE, MEDLINE, Veterinary Science Database
  • Sayfa Sayıları: ss.2090-2098
  • Anahtar Kelimeler: alpha defensin, COVID-19, IL-18, IL-1Ra, VIRUS
  • Atatürk Üniversitesi Adresli: Evet

Özet

Background Many laboratory parameters have been associated with morbidity and mortality in SARS-CoV-2 (COVID-19), which emerged in an animal market in Wuhan, China in December 2019 and has infected over 20 million people. This study investigated the relationship between serum interleukin (IL)-18, IL-1 receptor antagonist (IL-1Ra), and alpha defensin levels and the clinical course and prognosis of COVID-19.