Investigation of the Relationship of Some Antihypertensive Drugs with Oxidant/Antioxidant Parameters and DNA Damage on Rat Uterus Tissue
INTERNATIONAL JOURNAL OF FERTILITY & STERILITY, cilt.5, sa.2, ss.96-103, 2011 (SCI-Expanded, Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 5 Sayı: 2
- Basım Tarihi: 2011
- Dergi Adı: INTERNATIONAL JOURNAL OF FERTILITY & STERILITY
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
- Sayfa Sayıları: ss.96-103
- Anahtar Kelimeler: Antihypertensive, Oxidant/Antioxidant Parameters, DNA Damage, GASTRIC-MUCOSAL INJURY, LIPID-PEROXIDATION, OXIDATIVE STRESS, FREE-RADICALS, MECHANISM, ANTIOXIDANTS, 8-OXOGUANINE, GLUTATHIONE, ESTROGEN, DISEASE
- Atatürk Üniversitesi Adresli: Evet
Özet
Background: In this study, we investigated the effects of treatment with chronic antihypertensive drugs (clonidine, methyldopa, amlodipine, ramipril and rilmenidine) on oxidant-antioxidant parameters and toxic effects on DNA in rat uterus tissue. In addition, uterus tissues were examined histopathologically.