Metabolomic profiling in ankylosing spondylitis using time-of-flight mass spectrometry

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DOĞAN H. O., ŞENOL O., KARADAĞ A., Yildiz S. N.

CLINICAL NUTRITION ESPEN, cilt.50, ss.124-132, 2022 (ESCI) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 50
  • Basım Tarihi: 2022
  • Doi Numarası: 10.1016/j.clnesp.2022.06.011
  • Dergi Adı: CLINICAL NUTRITION ESPEN
  • Derginin Tarandığı İndeksler: Emerging Sources Citation Index (ESCI), Scopus, CAB Abstracts, EMBASE, Food Science & Technology Abstracts, MEDLINE, Veterinary Science Database
  • Sayfa Sayıları: ss.124-132
  • Anahtar Kelimeler: Ankylosing spondylitis, Fatty acid, Metabolomics, Phosphatidylcholine, UPLC Q-TOF/MS, Plasma, BIOMARKERS
  • Atatürk Üniversitesi Adresli: Evet

Özet

Background & aims: Ankylosing spondylitis (AS) is an inflammatory disease associated with destructive changes in the skeleton and joints. The exact molecular mechanism of the disease has not been fully elucidated. This study aimed to determine metabolic differences between active AS patients and healthy controls to understand the molecular mechanism of AS.