Therapeutic plasma exchange in patients with thrombotic thrombocytopenic purpura: A retrospective multicenter study

KORKMAZ S., KEKLİK M., Sivgin S., YILDIRIM R., TOMBAK A., Kaya M. E., ...Daha Fazla

TRANSFUSION AND APHERESIS SCIENCE, cilt.48, sa.3, ss.353-358, 2013 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 48 Sayı: 3
  • Basım Tarihi: 2013
  • Doi Numarası: 10.1016/j.transci.2013.04.016
  • Dergi Adı: TRANSFUSION AND APHERESIS SCIENCE
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.353-358
  • Anahtar Kelimeler: Thrombotic thrombocytopenic purpura, Therapeutic plasma exchange, Fresh frozen plasma, Complete response, HEMOLYTIC-UREMIC SYNDROME, SINGLE-CENTER EXPERIENCE, SYNDROME TTP-HUS, CLEAVING PROTEASE, IMPROVED SURVIVAL, MICROANGIOPATHIES, DEFICIENCY, RITUXIMAB, EFFICACY, STEROIDS
  • Atatürk Üniversitesi Adresli: Evet

Özet

Thrombotic thrombocytopenic purpura (TIT) is a particular form of thrombotic microangiopathy typically characterized by thrombocytopenia, microangiopathic hemolytic anemia, fever, neurological abnormalities, and renal dysfunction. UP requires a rapid diagnosis and an adapted management in emergency. Daily sessions of therapeutic plasma exchange (TPE) remain the basis of management of UP. Also, UP is a rare disease that is fatal if it is not treated. TPE has resulted in excellent remission and survival rates in UP patients.