Akademik Veri Yönetim Sistemi
International Conference on Physical Chemistry and Functional Materials, Elazığ, Türkiye, 19 - 21 Haziran 2018
Applications of nanomaterials in biosensors provide opportunities to develop next-generation biosensor technologies. Nanomaterials improve mechanical, electrochemical, optical and magnetic properties of biosensors and are developing towards biosensors with high selectivity and sensitivity. Ascorbic acid (AA) and dopamine (DA) play a significant role in the function of the central nervous, renal and hormonal systems. The deficiency or incompatibility of their levels may lead to the symptoms of many diseases such as cancer, Parkinson's disease and cardiovascular disease. Because of their electrochemical activity, AA and DA detection is always attracting the intense interest in electroanalysis.Unfortunately, AA is always coexisting with DA in organisms, sharing a similar oxidation potential in electrochemical detection. To overcome this problem, various carbon based materials including carbon nanotubes, carbon nanofibers and graphene have been combined with metals or metal oxides. Recent reports demonstrated that graphene based electrodes could be used to selectively determine DA in the existence of AA. In this study, we used a simple electrochemical method to fabricate the lead-oxide electrochemical reduced graphene oxide (PbOERGO) nanocomposites by electrochemical reduction of graphene oxide and Pb on Au(111) electrode. Then PbO-ERGO electrodes used as electrocatalyst for biosensors. Results show that Pb-ERGO nanocomposites have potential application as a heterogeneous catalyst support in biosensors.