ADVANCES IN CLINICAL AND EXPERIMENTAL MEDICINE, cilt.30, sa.5, ss.517-524, 2021 (SCI-Expanded)
Background. Periodontitis, a chronic inflammatory disease affecting the supporting tissues around the teeth, causes significant inflammatory and oxidative changes in cardiac tissue. Crocin is the active constituent of Crocus sativus (saffron) which has antioxidant properties and is protective against cardiovascular disturbances.