Evaluation of Cytotoxic Potentials of Some Isoindole-1, 3-Dione Derivatives on HeLa, C6 and A549 Cancer Cell Lines

Tan A., Yaglioglu A. S., KİSHALI N., ŞAHİN E., KARA Y.

MEDICINAL CHEMISTRY, cilt.16, sa.1, ss.69-77, 2020 (SCI-Expanded) identifier identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 16 Sayı: 1
  • Basım Tarihi: 2020
  • Doi Numarası: 10.2174/1573406415666181206115638
  • Dergi Adı: MEDICINAL CHEMISTRY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Agricultural & Environmental Science Database, Biotechnology Research Abstracts, EMBASE, MEDLINE
  • Sayfa Sayıları: ss.69-77
  • Anahtar Kelimeler: Isoindoline-1, 3-dione, norcantharimide, anticancer activity, heLa cells, C6 cells, 5-fluorouracil, A549 cells, NORCANTHARIDIN ANALOGS, CONVENIENT SYNTHESIS, ANTICANCER ACTIVITY, CANTHARIMIDE
  • Atatürk Üniversitesi Adresli: Evet

Özet

Background: Norcantharimides are known as norcantharidine derivatives and contain an isoindole skeleton structure. Isoindole derivatives have positive effect on inflammatory pathologies including cancers.