Study on Commiphora mukul (Guggul) gum: Exploring the proximate composition and techno-functional properties and efficacy against obesity


Awari A., Kaushik D., ÖZ E., Proestos C., Brennan C., ÖZ F., ...Daha Fazla

International Journal of Food Science and Technology, cilt.60, sa.2, 2025 (SCI-Expanded, Scopus) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 60 Sayı: 2
  • Basım Tarihi: 2025
  • Doi Numarası: 10.1093/ijfood/vvaf157
  • Dergi Adı: International Journal of Food Science and Technology
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, BIOSIS, Chemical Abstracts Core, Compendex, Directory of Open Access Journals
  • Anahtar Kelimeler: bioactive compounds, Commiphora mukul, functional food, obesity management, phytochemical analysis, α-amylase inhibition
  • Atatürk Üniversitesi Adresli: Evet

Özet

Commiphora mukul (guggul) gum has been widely utilised in traditional medicine for the treatment of obesity and metabolic disorders. This study explores its proximate composition, techno-functional properties, phytochemical content, and bioactivity to evaluate its potential as a functional food ingredient. Proximate analysis revealed low moisture (2.07%), moderate fat (17.43%), protein (9.77%), and ash content (6.73%), supporting its suitability for food applications. The gum exhibited favourable flow properties, with a bulk density of 0.63 g/cm3 and an angle of repose of 26.9°, facilitating its incorporation into formulations. Phytochemical analysis identified phenolic (6.91 mg GAE/g) and flavonoid (1.68 mg QE/g) contents, indicating antioxidant activity. In vitro assays revealed significant dose-dependent α-amylase and glucose inhibition, with an IC50 of 54.01 μg/ml, highlighting potential roles in carbohydrate metabolism regulation. These findings support C. mukul gum powder as a promising ingredient for functional foods and nutraceuticals targeting obesity and metabolic health.