Study on Commiphora mukul (Guggul) gum: Exploring the proximate composition and techno-functional properties and efficacy against obesity
International Journal of Food Science and Technology, cilt.60, sa.2, 2025 (SCI-Expanded, Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 60 Sayı: 2
- Basım Tarihi: 2025
- Doi Numarası: 10.1093/ijfood/vvaf157
- Dergi Adı: International Journal of Food Science and Technology
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, BIOSIS, Chemical Abstracts Core, Compendex, Directory of Open Access Journals
- Anahtar Kelimeler: bioactive compounds, Commiphora mukul, functional food, obesity management, phytochemical analysis, α-amylase inhibition
- Atatürk Üniversitesi Adresli: Evet
Özet
Commiphora mukul (guggul) gum has been widely utilised in traditional medicine for the treatment of obesity and metabolic disorders. This study explores its proximate composition, techno-functional properties, phytochemical content, and bioactivity to evaluate its potential as a functional food ingredient. Proximate analysis revealed low moisture (2.07%), moderate fat (17.43%), protein (9.77%), and ash content (6.73%), supporting its suitability for food applications. The gum exhibited favourable flow properties, with a bulk density of 0.63 g/cm3 and an angle of repose of 26.9°, facilitating its incorporation into formulations. Phytochemical analysis identified phenolic (6.91 mg GAE/g) and flavonoid (1.68 mg QE/g) contents, indicating antioxidant activity. In vitro assays revealed significant dose-dependent α-amylase and glucose inhibition, with an IC50 of 54.01 μg/ml, highlighting potential roles in carbohydrate metabolism regulation. These findings support C. mukul gum powder as a promising ingredient for functional foods and nutraceuticals targeting obesity and metabolic health.