Biological evaluation and structure-activity relationships of bis-(3-aryl-3-oxo-propyl)-methylamine hydrochlorides and 4-aryl-3-arylcarbonyl-1-methyl-4-piperidinol hydrochlorides as potential cytotoxic agents and their alkylating ability towards cellular glutathione in human leukemic T cells.


Gul M., GUL H. İ., DAS U., HANNINEN O.

Arzneimittel-Forschung, cilt.55, ss.332-7, 2005 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 55
  • Basım Tarihi: 2005
  • Doi Numarası: 10.1055/s-0031-1296868
  • Dergi Adı: Arzneimittel-Forschung
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.332-7
  • Anahtar Kelimeler: bis-Mannich bases, cytotoxicity, Jurkat cells, thiol alkylation, cytotoxic agents, piperidinols, cytotoxicity Jurkat cells, thiol alkylation, BIS-MANNICH-BASES, CORRESPONDING PIPERIDINOLS, JURKAT CELLS, ANTIMICROBIAL EVALUATION, MONO, ACETOPHENONES, DERIVATIVES, STABILITY, BIOASSAY
  • Atatürk Üniversitesi Adresli: Evet