The effect of rutin on experimentally induced acute heart contusion in rats: Biochemical and histopathological evaluation

Elma B., MAMMADOV R., SÜLEYMAN H., GÜNDOĞDU B., Yurt S., Bilgin Y., ...Daha Fazla

ULUSAL TRAVMA VE ACIL CERRAHI DERGISI-TURKISH JOURNAL OF TRAUMA & EMERGENCY SURGERY, cilt.28, sa.8, ss.1073-1081, 2022 (SCI-Expanded) identifier identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 28 Sayı: 8
  • Basım Tarihi: 2022
  • Doi Numarası: 10.14744/tjtes.2021.97760
  • Dergi Adı: ULUSAL TRAVMA VE ACIL CERRAHI DERGISI-TURKISH JOURNAL OF TRAUMA & EMERGENCY SURGERY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, CINAHL, EMBASE, MEDLINE, TR DİZİN (ULAKBİM)
  • Sayfa Sayıları: ss.1073-1081
  • Anahtar Kelimeler: Blunt thoracic trauma, heart contusion, rat, rutin, INDUCED OXIDATIVE STRESS, CARDIAC INJURY, IN-VITRO, ANTIOXIDANT, INFLAMMATION, QUERCETIN, APOPTOSIS, TRAUMA, ISCHEMIA
  • Atatürk Üniversitesi Adresli: Evet

Özet

BACKGROUND: Acute cardiac contusion induced by trauma is known with its high mortality and morbidity. The role of oxidative stress and inflammation in its pathophysiology has led to the investigation of antioxidant and anti-inflammatory substances in non-surgical treatment. In this study, the effects of rutin which has these two features on acute cardiac contusion were investigated.