The Distribution of Apolipoprotein E Gene Polymorphism and Apolipoprotein E Levels among Coronary Artery Patients Compared to Controls


ATIŞ Ö., ŞAHİN Ş., Ceyhan K., Ozyurt H., Akbas A., Benli I.

EURASIAN JOURNAL OF MEDICINE, vol.48, no.2, pp.90-94, 2016 (ESCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 48 Issue: 2
  • Publication Date: 2016
  • Doi Number: 10.5152/eurasianjmed.2015.25
  • Journal Name: EURASIAN JOURNAL OF MEDICINE
  • Journal Indexes: Emerging Sources Citation Index (ESCI), Scopus, TR DİZİN (ULAKBİM)
  • Page Numbers: pp.90-94
  • Keywords: Coronary artery disease, apoE genotype, apoE level, MYOCARDIAL-INFARCTION, DENSITY-LIPOPROTEIN, E PHENOTYPE, ASSOCIATION, CHOLESTEROL, PROTEIN, DISEASE, RISK, FREQUENCIES, MORTALITY
  • Ataturk University Affiliated: Yes

Abstract

Objective: Coronary artery disease (CAD) is a multifactorial disease that is caused by various genetics and environmental factors. Genetically, predisposition is an important component for CAD. The candidate apolipoprotein E (apoE) gene is the most studied one. ApoE is composed of e2, e3, e4 alleles and E2/2, E2/3, E2/4, E3/3, E3/4, E4/4 genotypes. In this study, the relationship between CAD and apoE polymorphism and apoE level has been studied in Tokat region.