The Distribution of Apolipoprotein E Gene Polymorphism and Apolipoprotein E Levels among Coronary Artery Patients Compared to Controls

ATIŞ Ö., ŞAHİN Ş., Ceyhan K., Ozyurt H., Akbas A., Benli I.

EURASIAN JOURNAL OF MEDICINE, cilt.48, sa.2, ss.90-94, 2016 (ESCI) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 48 Sayı: 2
  • Basım Tarihi: 2016
  • Doi Numarası: 10.5152/eurasianjmed.2015.25
  • Dergi Adı: EURASIAN JOURNAL OF MEDICINE
  • Derginin Tarandığı İndeksler: Emerging Sources Citation Index (ESCI), Scopus, TR DİZİN (ULAKBİM)
  • Sayfa Sayıları: ss.90-94
  • Anahtar Kelimeler: Coronary artery disease, apoE genotype, apoE level, MYOCARDIAL-INFARCTION, DENSITY-LIPOPROTEIN, E PHENOTYPE, ASSOCIATION, CHOLESTEROL, PROTEIN, DISEASE, RISK, FREQUENCIES, MORTALITY
  • Atatürk Üniversitesi Adresli: Evet

Özet

Objective: Coronary artery disease (CAD) is a multifactorial disease that is caused by various genetics and environmental factors. Genetically, predisposition is an important component for CAD. The candidate apolipoprotein E (apoE) gene is the most studied one. ApoE is composed of e2, e3, e4 alleles and E2/2, E2/3, E2/4, E3/3, E3/4, E4/4 genotypes. In this study, the relationship between CAD and apoE polymorphism and apoE level has been studied in Tokat region.