The role of Bax/Bcl-2 and Nrf2-Keap-1 signaling pathways in mediating the protective effect of boric acid on acrylamide-induced acute liver injury in rats

Cengiz M., AYHANCİ A., Akkemik E., Sahin I. K., GÜR F., Bayrakdar A., ...Daha Fazla

LIFE SCIENCES, cilt.307, 2022 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 307
  • Basım Tarihi: 2022
  • Doi Numarası: 10.1016/j.lfs.2022.120864
  • Dergi Adı: LIFE SCIENCES
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier, BIOSIS, CAB Abstracts, Chimica, EMBASE, MEDLINE, Veterinary Science Database
  • Anahtar Kelimeler: Biochemical toxicity, Acrylamide, Boric acid, Molecular modeling, Liver damage, Rats, INDUCED OXIDATIVE STRESS, INDUCED TOXICITY, DAMAGE, BORON, INFLAMMATION, APOPTOSIS, CYTOKINES, EXPOSURE, RISK
  • Atatürk Üniversitesi Adresli: Evet

Özet

Introduction: This study aims to investigate whether boric acid (BA) can protect rats from acrylamide (AA)induced acute liver injury.