Simultaneous detection of sulfoxaflor and its metabolites, X11719474 and X11721061, in lettuce using a modified QuEChERS extraction method and liquid chromatography-tandem mass spectrometry

Kim S., Rahman M. M., Abd El-Aty A. M., Kabir M. H., Na T. W., Choi J., ...Daha Fazla

BIOMEDICAL CHROMATOGRAPHY, cilt.31, sa.6, 2017 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 31 Sayı: 6
  • Basım Tarihi: 2017
  • Doi Numarası: 10.1002/bmc.3885
  • Dergi Adı: BIOMEDICAL CHROMATOGRAPHY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Anahtar Kelimeler: half-life, lettuce, liquid chromatography-tandem mass spectrometry, QuEChERS, residues, sulfoxaflor, metabolites, CHIRAL NEONICOTINOID SULFOXAFLOR, SOLID-PHASE EXTRACTION, INSECTICIDE SULFOXAFLOR, DISSIPATION, RESIDUES, SOIL
  • Atatürk Üniversitesi Adresli: Hayır

Özet

An analytical method has been developed to quantify the residual levels of sulfoxaflor and its metabolites (X11719474 and X11721061) in/on cultivated lettuce grown under greenhouse conditions. Samples were extracted and purified using a quick, easy, cheap, effective, rugged, and safe QuEChERS' method (original version) following systematic method optimization and were analyzed by liquid chromatography-tandem mass spectrometry (LC-MS/MS). Good linearity with coefficient of determination 0.9930 was obtained and the limits of detection (LOD) and quantification (LOQ) were in the ranges of 0.003-0.006 and 0.01-0.02mg/kg, respectively. The recovery rates of both the parent compound and its metabolites (fortified at 10 and 50x the LOQ) estimated from six replicates ranged between 81.9 and 115.5% with a relative standard deviation <12%. The validated method was applied to field-incurred samples (collected over 7days) sprayed once or twice with a water-dispersible granule formulation. Notably, a substantial reduction in rate was observed after 3days and the half-life was short, only 1.5days. The developed method is simple and versatile and can be used for various leafy vegetables.