Evaluation of the Relationship Between Isometric Exercise and Roll-Over Tests and the Levels of Pregnancy-Associated Plasma Protein A and Beta-Human Chorionic Gonadotropin and Neutrophil–Lymphocyte Ratio in the Early Diagnosis of Preeclampsia


Kozacioglu Ugan O., EJDER APAY S.

Obstetrics and Gynecology International, vol.2026, no.1, 2026 (ESCI, Scopus)

  • Publication Type: Article / Article
  • Volume: 2026 Issue: 1
  • Publication Date: 2026
  • Doi Number: 10.1155/ogi/9393263
  • Journal Name: Obstetrics and Gynecology International
  • Journal Indexes: Emerging Sources Citation Index (ESCI), Scopus
  • Keywords: hypertension, midwife, NLR, PAPP-A, preeclampsia, β-hCG
  • Ataturk University Affiliated: Yes

Abstract

Objective: This study aimed to determine the relationship between isometric exercise test, roll-over test, levels of PAPP-A and β-hCG, and NLO in the early diagnosis of preeclampsia. Materials and Method: The 580 pregnant women filled out the personal information forms and performed the roll-over test and isometric exercise test. Results: The roll-over test and isometric exercise test used in the diagnosis of preeclampsia had high levels of sensitivity and specificity and negative predictive values. Conclusion: Thus, roll-over test and isometric exercise test, pregnancy-associated plasma protein A levels, and neutrophil–lymphocyte ratio are useful parameters for the early diagnosis of preeclampsia.