Ablation therapy with cyanoacrylate glue and laser for refluxing great saphenous veins - a prospective randomised study


ÇALIK E., ARSLAN Ü., ERKUT B.

VASA-EUROPEAN JOURNAL OF VASCULAR MEDICINE, cilt.48, sa.5, ss.405-412, 2019 (SCI-Expanded) identifier identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 48 Sayı: 5
  • Basım Tarihi: 2019
  • Doi Numarası: 10.1024/0301-1526/a000792
  • Dergi Adı: VASA-EUROPEAN JOURNAL OF VASCULAR MEDICINE
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.405-412
  • Anahtar Kelimeler: Chronic venous insufficiency, varicose veins, ablation, cyanoacrylate, laser, N-BUTYL CYANOACRYLATE, RADIOFREQUENCY ABLATION, VARICOSE-VEINS, EMBOLIZATION, ADHESIVE, SCLEROTHERAPY, MULTICENTER, GUIDELINES, CLOSURE
  • Atatürk Üniversitesi Adresli: Evet

Özet

Background: Endovenous cyanoacrylate ablation is a new technique for the treatment of clinically symptomatic venous insufficiency. The results of a prospective comparative study of cyaroacrylate glue versus endovenous laser ablation for the management of incompetent great sapherous veins are presented. Patients and methods: A total of 400 subjects were treated with cyanoacrylate ablation or endovenous laser ablation between April 2014 and April 2016. The preprocedural, procedural, postprocedural, and follow up data were recorded and compared. Results: There were 208 procedures in cyanoacrylate ablation group (CM) and 204 in endovenous laser ablation group (EVLA). Operative time was 13 +/- 3.4 minutes in the CAA and 31.7 +/- 8.8 minutes in the EVLA 0.001). All procedures in both groups were successful, and the target vein segments were fully occluded at the end e the procedure. Periprocedural pair was less in the CAA (< 0.001). Enduration, ecchymosis, and paresthesia rates were significantly higher it the EVLA (< 0.001). The mean length of follow-up was 14 months (range 10-16). The 3, 6 and 12 months closure rates were 97.4%, 95.6%, and 94.1% for EVLA and 98.6%, 97.1% and 96.6% for CAA respectively. In both groups, the Venous Clinical Severity Score and Chronic Venous Insufficiency Quality of Life Questionnaire with declined significantly with no difference between groups. Conclusions: Management of incompetent great saphenous veins both endovenous cyanoacrylate ablation and laser ablation results in high occlusion rates. Endovenous cyanoacrylate ablation technique is fast and simple with low periprocedural pain that does not require tumescent anesthesia and compression stockings.