Paracetamol sensing with a flexible graphene paper electrode modified with MnCo2O4

Shafiyev M., Erçarıkcı E., Dağcı Kıranşan K., Topçu E.

JOURNAL OF CHEMICAL TECHNOLOGY AND BIOTECHNOLOGY, cilt.99, sa.12, ss.2582-2591, 2024 (SCI-Expanded) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 99 Sayı: 12
  • Basım Tarihi: 2024
  • Doi Numarası: 10.1002/jctb.7739
  • Dergi Adı: JOURNAL OF CHEMICAL TECHNOLOGY AND BIOTECHNOLOGY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Aerospace Database, Applied Science & Technology Source, Aqualine, Aquatic Science & Fisheries Abstracts (ASFA), BIOSIS, Biotechnology Research Abstracts, CAB Abstracts, Chemical Abstracts Core, Chimica, Communication Abstracts, Compendex, Computer & Applied Sciences, Food Science & Technology Abstracts, INSPEC, Metadex, Pollution Abstracts, Veterinary Science Database, Civil Engineering Abstracts
  • Sayfa Sayıları: ss.2582-2591
  • Atatürk Üniversitesi Adresli: Evet

Özet

BACKGROUND: The design of new-generation flexible sensors for medical applications has gained considerable interest in the research community in recent past years. Herein, a free-standing flexible electrode was developed for the electrochemical determination of Paracetamol (PC). This graphene-based paper electrode was prepared using graphene and MnCo2O4 dispersion with a mold-casting method followed by chemical reduction. The morphology and structure of our flexible paper electrode (MnCo2O4/GP) were characterized by scanning electron microscopy, energy-dispersive, X-ray diffraction, X-ray photoelectron, and Raman spectroscopy. RESULTS: The as-prepared flexible MnCo2O4/GP showed outstanding sensing performance for PC, as compared to GP, due to the excellent electrochemical properties of MnCo2O4. The proposed sensor exhibited a wide linear range of 4.64-1000 mu M for electrochemical determination of PC with a low detection limit of 1.39 mu M. Furthermore, MnCo2O4/GP was successfully applied for PC syrup and tablets with good accuracy results. CONCLUSIONS: For the first time, the present study demonstrated the fabrication and utilization of MnCo2O4-modified graphene paper to develop a flexible and sensitive electrode for monitoring PC. (c) 2024 The Author(s). Journal of Chemical Technology and Biotechnology published by John Wiley & Sons Ltd on behalf of Society of Chemical Industry (SCI).