Efficacy of boric acid therapy in a pseudomonas aeruginosa- induced chronic otitis media model in rats

Şahin A., Kars A., Kılıç K., Sakat M. S., Köyceğiz S., Yildirim S.

CUKUROVA MEDICAL JOURNAL, cilt.47, sa.3, ss.1163-1171, 2022 (ESCI) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 47 Sayı: 3
  • Basım Tarihi: 2022
  • Doi Numarası: 10.17826/cumj.1126208
  • Dergi Adı: CUKUROVA MEDICAL JOURNAL
  • Derginin Tarandığı İndeksler: Emerging Sources Citation Index (ESCI), Academic Search Premier, Directory of Open Access Journals, TR DİZİN (ULAKBİM)
  • Sayfa Sayıları: ss.1163-1171
  • Anahtar Kelimeler: Boric acid, chronic otitis media, pseudomonas aeruginosa, rat, tumor necrosis factor-alpha, ANTISEPTICS
  • Atatürk Üniversitesi Adresli: Evet

Özet

Purpose: Chronic otitis media (COM) is one of the common infectious diseases of the middle ear caused by bacterial or viral pathogens. The purpose of the present study was to investigate the efficacy of boric acid (BA) in the treatment of COM by comparing topical 4% and 8% BA applications with systemic ciprofloxacin in a Pseudomonas aeruginosa (P. aeruginosa) inoculation-induced model of COM in rats.