What do simple hematological parameters tell us in patients with systemic sclerosis?

Tezcan D., Turan C., YILMAZ S., SİVRİKAYA A., Gulcemal S., Limon M., ...More

ACTA DERMATOVENEROLOGICA ALPINA PANNONICA ET ADRIATICA, vol.29, no.3, pp.101-107, 2020 (ESCI) identifier identifier identifier


Introduction: Systemic sclerosis (SSc) or scleroderma is a clinically heterogeneous disease. Autoantibodies associated with different clinical features may help in predicting organ involvement. Complete blood count (CBC) parameters and neutrophil/lymphocyte (NLR), monocyte/lymphocyte (MLR), and platelet/lymphocyte (PLR) ratios, which are considered biomarkers of systemic inflammation, have been reported many times in various rheumatologic diseases. Studies related to the usefulness of the CBC to assess the severity of SSc are still lacking. This study seeks to determine whether CBC parameters associated with organ involvement, when evaluated together with clinical features and autoantibodies, can additionally contribute to risk estimation.