Comparative plasma disposition of fenbendazole, oxfendazole and albendazole in dogs

GÖKBULUT C., BİLGİLİ A., Hanedan B., McKellar Q. A.

VETERINARY PARASITOLOGY, cilt.148, ss.279-287, 2007 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 148
  • Basım Tarihi: 2007
  • Doi Numarası: 10.1016/j.vetpar.2007.06.028
  • Dergi Adı: VETERINARY PARASITOLOGY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.279-287
  • Anahtar Kelimeler: pharmacokinetics, fenbendazole, oxfendazole, albendazole, benzimidazoles, dog, BENZIMIDAZOLE ANTHELMINTICS, HAEMONCHUS-CONTORTUS, SULFOXIDE METABOLITE, SHEEP, EFFICACY, PHARMACOKINETICS, TUBULIN, BEHAVIOR, DRUGS, ABSORPTION
  • Atatürk Üniversitesi Adresli: Hayır

Özet

The plasma disposition of fenbendazole (FBZ), oxfendazole (OFZ) and albendazole (ABZ); and the enantiospecific disposition of OFZ, and ABZSO produced were investigated following an oral administration (50 mg/kg) in dogs. Blood samples were collected from I to 120 h post-administration. The plasma samples were analysed by high performance liquid chromatography (HPLC).