ORAL SURGERY, ORAL MEDICINE, ORAL PATHOLOGY, ORAL RADIOLOGY, AND ENDODONTICS, cilt.119, sa.3, ss.207-208, 2015 (SCI-Expanded)
Pemphigus vulgaris (PV) is an autoimmune blistering disease
of the skin and mucosa. The classic presentations of PV are
flaccid vesicles or bullae over the oral mucosa, trunk, groin, and
extremities. Pemphigus vulgaris affects the oral mucosa in nearly
all cases. We report here two case of pemphigus vulgaris of
gingiva in an adult female patient at an early stage followed by
dermatologic involvement. Perilesional incision was taken and
histopathological and direct immunofluorescence was done for identification of specific antibodies. However, PV was confirmed
by hematoxylin and eosin staining and immunofluorescence examination of the skin biopsy specimens.
Keywords: Pemphigus vulgaris, oral mucosa, direct immunofluorescence