THE SYNERGISTIC ANTIMICROBIAL EFFECTS OF SOME PLANT HYDROSOLS IN COMBINATION WITH ANTIBIOTICS AGAINST FISH PATHOGENIC PSEUDOMONAS PUTIDA
16TH AZERBAIJAN CONGRESS ON LIFE, ENGINEERING,MATHEMATICAL, AND APPLIED SCIENCES, Baku, Azerbaycan, 20 - 22 Eylül 2026, ss.618-626, (Tam Metin Bildiri)
- Yayın Türü: Bildiri / Tam Metin Bildiri
- Basıldığı Şehir: Baku
- Basıldığı Ülke: Azerbaycan
- Sayfa Sayıları: ss.618-626
- Atatürk Üniversitesi Adresli: Evet
Özet
Bacterial fish diseases are among the greatest threats encountered in sustainable fish production. In the
event of a bacterial disease outbreak at fish farms, the first measure that comes to mind is the use of
antibiotics against the disease. In recent years, the intensive, unnecessary, and excessive use of
antibiotics in fish farms has led to antibiotic resistance; this situation not only complicates the prevention
of bacterial diseases but also causes serious public health problems due to the transmission of resistance
genes to humans consuming the fish. These adverse issues associated with antibiotic use have recently
drawn the attention of researchers to the use of various products derived from aromatic plants known to
possess antimicrobial properties. Plant essential oils have long been used as alternatives to antibiotics.
When essential oils are obtained from plants using various distillation methods, plant hydrosols are also
produced alongside the essential oils. In this study, the synergistic effects of hydrosols obtained from
various plants on antibiotics frequently used against bacterial fish diseases were investigated. In the
study, Pseudomonas putida bacterium which cause Pseudomoniasis infections in fish and are known to
result in high mortality rates on farms was used. An evaluation of the results revealed that the efficacy
of the tested antibiotics was significantly enhanced against Pseudomonas putida when combined with
specific hydrosols. Specifically, synergistic effects were observed for florfenicol (with Foeniculum
vulgare), oxytetracycline (with Achillea millefolium and Alkanna tinctoria), chlortetracycline (with
Foeniculum vulgare and Achillea millefolium), gentamicin (with Foeniculum vulgare, Achillea
millefolium, and Laurus nobilis), chloramphenicol (with Ocimum basilicum), and erythromycin (with
Foeniculum vulgare, Alkanna tinctoria, and Ocimum basilicum). In Conclusion, results suggest that
hydrosols derived from aromatic plants byproducts of essential oil production that are often undervalued
and frequently toughed as waste, can enhance the efficacy of certain antibiotics. This beneficial effect
is significant, as it could potentially improve antibiotic performance and allow for reduced dosages.
Further research is needed to substantiate the potential of these eco-friendly products to serve as
alternatives to antibiotics or to function independently as antimicrobial agents.