Curcumin analogue 1,5-bis(4-hydroxy-3-((4-methylpiperazin-1-yl)methyl)phenyl)penta-1,4-dien-3-one mediates growth arrest and apoptosis by targeting the PI3K/AKT/mTOR and PKC-theta signaling pathways in human breast carcinoma cells.

Badr G., GUL H. İ., YAMALI C., MOHAMED A., BADR B., Gul M., ...Daha Fazla

Bioorganic chemistry, cilt.78, ss.46-57, 2018 (SCI-Expanded, Scopus)

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 78
  • Basım Tarihi: 2018
  • Doi Numarası: 10.1016/j.bioorg.2018.03.006
  • Dergi Adı: Bioorganic chemistry
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.46-57
  • Anahtar Kelimeler: Apoptosis, Breast cancer, Cell signaling, Curcumin analogue, Cyclin, Cytoskeleton, RHO GTPASES, CYCLE ARREST, CANCER, EXPRESSION, INHIBITION, INVASION, PROTEIN, PHASE, D1, PROLIFERATION
  • Atatürk Üniversitesi Adresli: Evet