Relationship Between Red Cell Distribution Width and Stroke in Patients With Stable Chronic Heart Failure: A Propensity Score Matching Analysis


Kaya A., Isik T., Kaya Y., ENGİNYURT Ö., GÜNAYDIN Z. Y., Iscanli M. D., ...More

CLINICAL AND APPLIED THROMBOSIS-HEMOSTASIS, vol.21, no.2, pp.160-165, 2015 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 21 Issue: 2
  • Publication Date: 2015
  • Doi Number: 10.1177/1076029613493658
  • Journal Name: CLINICAL AND APPLIED THROMBOSIS-HEMOSTASIS
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.160-165
  • Keywords: stroke, heart failure, red cell distribution width, PROGNOSTIC MARKER, SINUS RHYTHM, URIC-ACID, RISK, ATHEROSCLEROSIS, METAANALYSIS, ASSOCIATION, PREDICTION, DIAGNOSIS, RDW
  • Ataturk University Affiliated: Yes

Abstract

Aim: We aimed to investigate the association between baseline red cell distribution width (RDW) level and the risk of stroke in patients with heart failure (HF). Methods: A total of 153 consecutive patients with HF (New York Heart Association [NYHA] I-III and left ventricular ejection fraction of < 40%) were included in this prospective study. All the patients were followed up for 1 year, and during this period the cerebrovascular disease was questioned. Results: In matched population, using propensity score matching comparing patients with HF having stroke with patients without stroke, we found significantly increased basal RDW and serum uric acid. The receiver-operating characteristic curves of RDW for predicting stroke are performed. An RDW >= 15.2% measured on admission had 87% sensitivity and 74% specificity in predicting stroke in patients with HF (area under the curve: 0.923, 95% confidence interval: 0.852-0.994, P <.001). Conclusion: In conclusion, this study demonstrated that RDW may be important hematological indices for stroke in patients with HF using propensity score analysis.