The cytogenetic effects of the aqueous extracts of migratory locust ( Locusta migratoria L.) in vitro

Turkez H., İNCEKARA Ü., Guner A., AYDIN E., Dirican E., TOGAR B.

TOXICOLOGY AND INDUSTRIAL HEALTH, cilt.30, sa.3, ss.233-237, 2014 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 30 Sayı: 3
  • Basım Tarihi: 2014
  • Doi Numarası: 10.1177/0748233712452610
  • Dergi Adı: TOXICOLOGY AND INDUSTRIAL HEALTH
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.233-237
  • Anahtar Kelimeler: Chromosome aberration, genotoxicity, human lymphocytes, Locusta migratoria, micronucleus, sister chromatid exchange, WHOLE-BLOOD CULTURES, BORON-COMPOUNDS, BORIC-ACID, EDIBLE INSECTS, AFLATOXIN B-1, GENOTOXICITY, LYMPHOCYTES, TOXICITY, ABERRATIONS, POTENTIALS
  • Atatürk Üniversitesi Adresli: Evet

Özet

One of the useful and most commonly cultivated commercially species, migratory locust (Locusta migratoria; Orthoptera), was investigated in light of genotoxic damage potentials. For this aim, we evaluated the genotoxic potentials of water soluble extracts of L. migratoria on cultured human blood cells. The micronucleus, sister chromatid exchange and structural chromosome aberration assays were applied to assess DNA and chromosomal damage produced by aqueous extracts in vitro. The extracts were added to the cultures at different concentrations ranging from 0 to 1000mg/L. Our results indicated that these extracts did not exhibit genotoxicity at tested concentrations. We conclude that this in vitro approach for biomonitoring genotoxicity assessment is useful for comparing the potential health risks of edible insects.