Some Bioactivities of <i>Limonium meyeri</i> Extracts and their Separated Compounds

Sami M., Karaoğlan E., HANCI H., KAZAZ C.

BIORESOURCES, cilt.20, sa.1, ss.2171-2182, 2025 (SCI-Expanded, Scopus) identifier identifier

  • Yayın Türü: Makale / Derleme
  • Cilt numarası: 20 Sayı: 1
  • Basım Tarihi: 2025
  • Doi Numarası: 10.15376/biores.20.1.2171-2182
  • Dergi Adı: BIORESOURCES
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier, Agricultural & Environmental Science Database, CAB Abstracts, Chemical Abstracts Core, Compendex, Veterinary Science Database, Directory of Open Access Journals
  • Sayfa Sayıları: ss.2171-2182
  • Anahtar Kelimeler: Antimicrobial, Antityrosinase, Apigenin-7-O-β-glucuronide, Limonium meyeri, Myricetin 3-O-α-rhamnoside
  • Atatürk Üniversitesi Adresli: Evet

Özet

The antimicrobial and tyrosinase enzyme inhibition activities of various extracts and isolated compounds of Limonium meyeri were investigated. Apigenin-7-O-beta-glucuronide and myricetin 3-O-alpha-rhamnoside were isolated from the ethyl acetate fraction using chromatographic methods. Methanol extract showed 62.0% and ethyl acetate extract showed 57.6% tyrosinase enzyme inhibition activities at 400 mu g/mL concentration. Myricetin 3-O-alpha-rhamnoside (IC50 = 27.7 +/- 0.6 mu g/mL) showed higher tyrosinase enzyme inhibitory effect than apigenin-7-O-beta-glucuronide (IC50 = 43.0 +/- 0.9 mu g/mL). n-Hexane extract was found to be effective against Enterococcus faecalis (MIC = 1 mu g/mL), while methanol extract was effective against Pseudomonas aeruginosa (MIC = 16 mu g/mL). Myricetin 3-O-alpha-rhamnoside showed antimicrobial effect against Enterococcus faecalis (MIC = 128 mu g/mL). Thus, Limonium meyeri and its compounds may provide valuable insights for future studies as antityrosinase and antibacterial agents.