The Effects of Agomelatine Treatment on Lipopolysaccharide-Induced Septic Lung Injuries in Rats

KÖSE D., Yuksel T. N., HALICI Z., ÇADIRCI E., GÜRBÜZ M. A.

EURASIAN JOURNAL OF MEDICINE, cilt.53, sa.2, ss.127-131, 2021 (ESCI, Scopus, TRDizin)

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 53 Sayı: 2
  • Basım Tarihi: 2021
  • Doi Numarası: 10.5152/eurasianjmed.2021.20342
  • Dergi Adı: EURASIAN JOURNAL OF MEDICINE
  • Derginin Tarandığı İndeksler: Emerging Sources Citation Index (ESCI), Scopus, Academic Search Premier, CINAHL, Directory of Open Access Journals, TR DİZİN (ULAKBİM)
  • Sayfa Sayıları: ss.127-131
  • Anahtar Kelimeler: Sepsis, agomelatine, tumor necrosis factor-alpha, nuclear factor-kappa B, MELATONIN RECEPTOR, ANIMAL-MODELS, MT2 RECEPTORS, SEPSIS, GENES
  • Atatürk Üniversitesi Adresli: Evet

Özet

Objective: We designed an experimental model of sepsis in rats to investigate the effects of agomelatine (AGO) on lung tissues using molecular and histopathological methods.