Matrix metalloproteinase inhibitor and sunscreen effective compounds from Rumex crispus L.: isolation, identification, bioactivity and molecular docking study


UZUN M., GÜVENALP Z., KAZAZ C., DEMİREZER L. Ö.

PHYTOCHEMICAL ANALYSIS, cilt.31, sa.6, ss.818-834, 2020 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 31 Sayı: 6
  • Basım Tarihi: 2020
  • Doi Numarası: 10.1002/pca.2948
  • Dergi Adı: PHYTOCHEMICAL ANALYSIS
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Agricultural & Environmental Science Database, Analytical Abstracts, Aquatic Science & Fisheries Abstracts (ASFA), BIOSIS, CAB Abstracts, Chemical Abstracts Core, Chimica, EMBASE, MEDLINE, Veterinary Science Database
  • Sayfa Sayıları: ss.818-834
  • Anahtar Kelimeler: anti-ageing, matrix metalloproteinase inhibitor, molecular docking, Rumex crispus L, sun protection factor, NAPHTHALENE GLYCOSIDES, ANTHRAQUINONES, DERIVATIVES, MECHANISMS, SPEED, ROOTS
  • Atatürk Üniversitesi Adresli: Evet

Özet

Introduction Rumex (Polygonaceae) species are widely grown worldwide and their main compounds are anthranoids, tannins, naphthalenes and flavonoids. Matrix metalloproteinase (MMP) enzymes that cause the breakdown of the extracellular matrix and harmful ultraviolet (UV) rays are two important causes of skin ageing. Although there have been many studies on anthraquinones, there are not many studies on their anti-ageing effects.