Protective effect of curcumin against contrast induced nephropathy in rat kidney: What is happening to oxidative stress, inflammation, autophagy and apoptosis?

Buyuklu M., Kandemir F. M., Ozkaraca M., Set T., Bakırcı E., Topal E.

European Review for Medical and Pharmacological Sciences, cilt.18, sa.4, ss.461-470, 2014 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 18 Sayı: 4
  • Basım Tarihi: 2014
  • Dergi Adı: European Review for Medical and Pharmacological Sciences
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.461-470
  • Anahtar Kelimeler: Angiography, Nephropathy, Curcumin, Contrast, Autophagy, Apoptosis, NITRIC-OXIDE SYNTHASE, N-ACETYLCYSTEINE, DIABETIC-NEPHROPATHY, RENAL-INSUFFICIENCY, SODIUM-BICARBONATE, INDUCED TOXICITY, CELL APOPTOSIS, PREVENTION, MEDIA, ANTIOXIDANT
  • Atatürk Üniversitesi Adresli: Evet

Özet

BACKGROUND: Currently, the number of imaging and interventional procedures that use contrast agents (CAs) is gradually increasing. Oxidative stress plays a significant role in its pathophysiology. Curcumin (CC) is a natural substance with strong antioxidant efficacy.