Docking Studies and Antiproliferative Activities of 6-(3-aryl-2-propenoyl)-2(3H)-benzoxazolone Derivatives as Novel Inhibitors of Phosphatidylinositol 3-Kinase (PI3K alpha)
ANTI-CANCER AGENTS IN MEDICINAL CHEMISTRY, cilt.21, sa.6, ss.716-724, 2021 (SCI-Expanded, Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 21 Sayı: 6
- Basım Tarihi: 2021
- Doi Numarası: 10.2174/1871520620666200807221731
- Dergi Adı: ANTI-CANCER AGENTS IN MEDICINAL CHEMISTRY
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Biotechnology Research Abstracts, Chemical Abstracts Core, EMBASE, MEDLINE
- Sayfa Sayıları: ss.716-724
- Anahtar Kelimeler: Molecular docking, PI3K alpha, colon cancer, apoptosis, chalcone, LDH
- Atatürk Üniversitesi Adresli: Evet
Özet
Background: Cancer is a life-threatening group of diseases and universally, the second main cause of death. The design and development of new scaffolds targeting selective cancer cells are considered a promising goal for cancer treatment.