Determination of the Effects of Genistein on the Longevity of Drosophila melanogaster Meigen (Diptera; Drosophilidae)

Altun D., UYSAL H., AŞKIN H., Ayar A.

BULLETIN OF ENVIRONMENTAL CONTAMINATION AND TOXICOLOGY, cilt.86, sa.1, ss.120-123, 2011 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 86 Sayı: 1
  • Basım Tarihi: 2011
  • Doi Numarası: 10.1007/s00128-010-0159-x
  • Dergi Adı: BULLETIN OF ENVIRONMENTAL CONTAMINATION AND TOXICOLOGY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.120-123
  • Anahtar Kelimeler: Aging, Drosophila melanogaster, Genistein, Longevity, PHYTO-ESTROGENS, IN-VITRO, PHYTOESTROGENS, METABOLISM, STRESS
  • Atatürk Üniversitesi Adresli: Evet

Özet

In this study, the effects of genistein on the longevity of Drosophila melanogaster were investigated. The effects of different concentrations of genistein (1, 3, 5 and 10 mu M/100 mL medium) were separately administered one by one to female and male populations of D. melanogaster for application groups. In the control group, the maximum life span was determined to be 57 days for a (TM) Euroa (TM) Euro, 46 for a (TM),a (TM),. The maximum life span for the lowest (1.0 mu L) and highest (10.0 mu L) application groups among the adult populations of D. melanogaster subjected to genistein were observed to be 54, 50, 40 and 36 days for a (TM) Euroa (TM) Euro and 51, 48, 40 and 33 days for a (TM),a (TM),. These values indicate a negative correlation (R = 0.513 for a (TM),a (TM), and R = 0.509 for a (TM) Euroa (TM) Euro) between the maximum life span of the application groups and changing genistein concentrations.