Epigallocatechin-3-gallate (EGCG) exert therapeutic effect on acute inflammatory otitis media in rats

KAYA, Zülküf; YAYLA, MUHAMMED; Cinar, Irfan; Atila, Nihal; ÖZMEN, Sevilay; BAYRAKTUTAN, Zafer; Bilici, Dilek

doi:10.1016/j.ijporl.2019.05.012

Epigallocatechin-3-gallate (EGCG) exert therapeutic effect on acute inflammatory otitis media in rats

KAYA Z., YAYLA M., Cinar I., Atila N. E., ÖZMEN S., BAYRAKTUTAN Z., ...Daha Fazla

INTERNATIONAL JOURNAL OF PEDIATRIC OTORHINOLARYNGOLOGY, cilt.124, ss.106-110, 2019 (SCI-Expanded, Scopus)

Yayın Türü: Makale / Tam Makale
Cilt numarası: 124
Basım Tarihi: 2019
Doi Numarası: 10.1016/j.ijporl.2019.05.012
Dergi Adı: INTERNATIONAL JOURNAL OF PEDIATRIC OTORHINOLARYNGOLOGY
Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Sayfa Sayıları: ss.106-110
Anahtar Kelimeler: EGCG, Inflammation, LPS, Otitis media, Rat, ALPHA, LIPOPOLYSACCHARIDE, VIRULENCE, ACID
Atatürk Üniversitesi Adresli: Evet

Özet

Introduction: That EGCG has strong antioxidant and anti-inflammatory activities as well as antibacterial activity against many streptococcus species suggests that it may be beneficial in the treatment of AOM. Objective: Aim of the study is to reveal the molecular and biochemical effects of EGCG on LPS induced otitis media in rats.