Epigallocatechin-3-gallate (EGCG) exert therapeutic effect on acute inflammatory otitis media in rats
INTERNATIONAL JOURNAL OF PEDIATRIC OTORHINOLARYNGOLOGY, vol.124, pp.106-110, 2019 (SCI-Expanded, Scopus)
- Publication Type: Article / Article
- Volume: 124
- Publication Date: 2019
- Doi Number: 10.1016/j.ijporl.2019.05.012
- Journal Name: INTERNATIONAL JOURNAL OF PEDIATRIC OTORHINOLARYNGOLOGY
- Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
- Page Numbers: pp.106-110
- Keywords: EGCG, Inflammation, LPS, Otitis media, Rat, ALPHA, LIPOPOLYSACCHARIDE, VIRULENCE, ACID
- Ataturk University Affiliated: Yes
Abstract
Introduction: That EGCG has strong antioxidant and anti-inflammatory activities as well as antibacterial activity against many streptococcus species suggests that it may be beneficial in the treatment of AOM. Objective: Aim of the study is to reveal the molecular and biochemical effects of EGCG on LPS induced otitis media in rats.