Serum YKL-40/chitinase 3-like protein 1 level is an independent predictor of atherosclerosis development in patients with obstructive sleep apnea syndrome

BAKIRCI E. M., ÜNVER E., DEĞİRMENCİ H., Kivanc T., Gunay M., HAMUR H., ...Daha Fazla

TURK KARDIYOLOJI DERNEGI ARSIVI-ARCHIVES OF THE TURKISH SOCIETY OF CARDIOLOGY, cilt.43, sa.4, ss.333-339, 2015 (ESCI) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 43 Sayı: 4
  • Basım Tarihi: 2015
  • Doi Numarası: 10.5543/tkda.2015.56805
  • Dergi Adı: TURK KARDIYOLOJI DERNEGI ARSIVI-ARCHIVES OF THE TURKISH SOCIETY OF CARDIOLOGY
  • Derginin Tarandığı İndeksler: Emerging Sources Citation Index (ESCI), Scopus, TR DİZİN (ULAKBİM)
  • Sayfa Sayıları: ss.333-339
  • Anahtar Kelimeler: Carotid intima-media thickness, coronary artery disease, inflammation, sleep apnea, obstructive, YKL-40, INTIMA-MEDIA THICKNESS, ENDOTHELIAL DYSFUNCTION, INFLAMMATORY MARKERS, YKL-40 LEVELS, SEVERITY, ASSOCIATION, DISEASE, RISK
  • Atatürk Üniversitesi Adresli: Evet

Özet

Objective: The inflammatory process plays an important role in the development of cardiovascular complications in patients with obstructive sleep apnea syndrome (OSAS). YKL-40/chitinase 3-like protein 1 is a novel biomarker of systemic inflammation. This study aimed to investigate whether carotid intima-media thickness (CIMT), a useful marker for early atherosclerosis, is associated with serum YKL-40/chitinase 3-like protein 1 levels in patients with normotensive and nondiabetic OSAS.