International Journal of Clinical Practice , cilt.2025, ss.1-6, 2025 (Hakemli Dergi)
Purpose: Patients with multiple sclerosis (MS) experience disabilities which signifcantly afect their quality of life (QOL). Anxiety,depressive, and disability symptoms are one of the most common psychiatric conditions in MS patients. Te aim of this study wasto evaluate the level of QOL in MS patients and to assess the impact of physical disability on QOL in an eastern province of Turkey.Methods: In this cross-sectional study used a questionnaire designed by the authors, which contained questions about soci-odemographic, as well as the following standardized questionnaires: Expanded Disability Status Scale (EDSS), Hospital Anxietyand Depression Scale (HADS) and QOL scale (WHOQOL-BREF) were used in 100 inpatients in the study.Results: Te average age of the patients was 35.5 ± 8.6 years and 68 (68.0%) were women. Te mean of EDSS scores was 2.05 ± 1.6(min-max: 0–6.5). 64% of the patients were married, 33% were university graduates, 43% were housewives, and 66% were middle-income. Mean scores for HAD_D and all WHOQOL-BREF domains decreased with income level, and there were signifcantdiferences between income groups (p < 0.05).Conclusion: Examining the relationships between depression, disability and QOL in people with MS highlights the psychosocialchallenges that these patients face in their daily lives. From a clinical practice perspective, these fndings support health pro-fessionals in conducting more comprehensive assessments of depression and QOL in people with MS. Healthcare professionalscan develop individualized treatment plans to improve patients’ QOL