Quantification of main secondary metabolites of Satureja icarica P.H. Davis (Lamiaceae) by LC-HRMS and evaluation of antioxidant capacities

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Kinoglu B. K., DİRMENCİ T., DEMİRKAYA MİLOĞLU F., GÜLÇİN İ., Goren A. C.

JOURNAL OF CHEMICAL METROLOGY, cilt.17, ss.199-214, 2023 (ESCI) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 17
  • Basım Tarihi: 2023
  • Doi Numarası: 10.25135/jcm.2311.2956
  • Dergi Adı: JOURNAL OF CHEMICAL METROLOGY
  • Derginin Tarandığı İndeksler: Emerging Sources Citation Index (ESCI), Scopus
  • Sayfa Sayıları: ss.199-214
  • Atatürk Üniversitesi Adresli: Evet

Özet

In this study, we determined antioxidant activity of Satureja icarica L. (Lamiaceae) which is used as a spice by the local population against 1,1-diphenyl-2-picryl-hydrazyl (DPPHGreek ano teleia), N,N-dimethyl-p-phenylenediamine radicals (DMPD center dot+), and 2,2-azino-bis-3-ethylbenzthiazoline-6-sulfonic acid (ABTS center dot+) as well as their ability to reduce Fe3+, Fe3+-TPTZ, and Cu2+. The antioxidant activities of both extracts were similar to those of standards in all assays. For instance, IC50 of S. icarica were for scavenging DPPH was 10.19 mu g/mL. The results of liquid chromatography-high resolution mass spectrometry (LC-HRMS) revealed that the main secondary metabolites in Satureja icarica were found to be as rosmarinic acid and luteolin-7-O-rutinoside.