Mesoporous silica-magnetite nanocomposites: Fabrication, characterisation and applications in biosciences
Microporous and Mesoporous Materials, cilt.120, sa.3, ss.246-251, 2009 (SCI-Expanded, Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 120 Sayı: 3
- Basım Tarihi: 2009
- Doi Numarası: 10.1016/j.micromeso.2008.11.012
- Dergi Adı: Microporous and Mesoporous Materials
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
- Sayfa Sayıları: ss.246-251
- Anahtar Kelimeler: Core-shell nanocomposites, Mesoporous silica-magnetite, Magnetic bioseparation
- Atatürk Üniversitesi Adresli: Hayır
Özet
Template assisted fabrication of magnetic mesoporous silica-magnetite nanocomposites and their performance in binding and elution of Salmon sperm DNA has been reported. The effect of reaction pH (10-2) during the fabrication of nanocomposites has been studied. All materials fabricated at various pH were characterised by XRD, TEM, FT-IR, nitrogen adsorption and magnetic susceptibility measurements. Fabrication at neutral pH (7) in the presence of a cationic surfactant (cetyl trimethyl ammonium bromide; CTAB) produced core-shell nanocomposites of quasi spherical and rod shaped morphologies with mesoporous (pore size ∼3.5 nm) silica shell and rhombic magnetite core. Fabrication at alkaline pH (10) produced monolithic mesoporous silica composites with embedded magnetite nanoparticles. Fabrication at acidic pH (4 and 2) produced a biphasic mixture of rhombic magnetite and amorphous silica rods. A similar fabrication at acidic pH (2) in the absence of CTAB produced a biphasic mixture of rhombic magnetite and spherical silica nanoparticles. All materials exhibited a high value of Salmon sperm DNA binding at physiological pH whereas elution value of DNA was observed to be dependent on the extent of silica coating on magnetite nanoparticles. © 2008 Elsevier Inc. All rights reserved.