Mysterious effects of olfactory pathway lesions on intestinal immunodeficiency targeting Peyer's patches: The first experimental study

FIRINCI B., ÇAĞLAR Ö., KARADENİZ E., AHISKALIOĞLU A., DEMİRCİ T., DUMLU AYDIN M. D.

MEDICAL HYPOTHESES, cilt.125, ss.31-36, 2019 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 125
  • Basım Tarihi: 2019
  • Doi Numarası: 10.1016/j.mehy.2019.02.032
  • Dergi Adı: MEDICAL HYPOTHESES
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.31-36
  • Anahtar Kelimeler: Peyer's patches, Olfactory bulb lesion, Intestinal immunity, CENTRAL-NERVOUS-SYSTEM, LYMPHOID-TISSUE, DENDRITIC CELLS, PARKINSONS-DISEASE, MARGINAL ZONE, VIRUS, GUT, AUTOIMMUNITY, HYPERPLASIA, DISORDERS
  • Atatürk Üniversitesi Adresli: Evet

Özet

Background. Although olfaction has been considered as important neuroimmunomodulatory foundation, there is no satisfying analytical information between neurohistomorphological features olfactory networks and intestinal immune system hardwares. We studied if the olfactory bulb lesions (OBL) may rely on histopathological features of intestinal lymphatic Peyer's patches in an animal model.