Effect of final irrigation with sodium hypochlorite at different temperatures on postoperative pain level and antibacterial activity: a randomized controlled clinical study

Karataş E., Ayaz N., Uluköylü E., Baltacı M. Ö., Adıgüzel A.

JOURNAL OF APPLIED ORAL SCIENCE, cilt.29, 2021 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 29
  • Basım Tarihi: 2021
  • Doi Numarası: 10.1590/1678-7757-2020-0502
  • Dergi Adı: JOURNAL OF APPLIED ORAL SCIENCE
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, EMBASE, MEDLINE, Directory of Open Access Journals
  • Anahtar Kelimeler: Sodium hypochlorite, Pain, Postoperative, Antibacterial activity, SYMPTOMATIC APICAL PERIODONTITIS, INTRACANAL CRYOTHERAPY, ANTIMICROBIAL ACTIVITY, ENTEROCOCCUS-FAECALIS, ENDODONTIC TREATMENT, CALCIUM HYDROXIDE, TEETH, INFECTION, CHLORHEXIDINE, INSTRUMENTATION
  • Atatürk Üniversitesi Adresli: Evet

Özet

Objective: To evaluate the effect of final irrigation of root canals with NaOCl solution at different temperatures on postoperative pain level and antimicrobial activity. Methodology: 45 patients were randomly divided into three groups using a web program according to the irrigation selected: NaOCl 2 degrees C, NaOCl 25 degrees C and NaOCl 45 degrees C. First root canal samples were collected before treatment (S1). After chemo-mechanical preparation, final irrigation was performed with the selected irrigant (NaOCl 2 degrees C, NaOCl 25 degrees C and NaOCl 45 degrees C) and second samples were collected (S2). Samples were subjected to quantitative real-time polymerase chain reaction to evaluate the levels of total bacteria. The root canal treatments were completed and the participants were given instructions to record postoperative pain levels at 24, 48 and 72 hours, 5 days and 1 week after treatment using a visual analog scale (VAS). Results: The reduction in the number of total bacterial cell equivalents from S1 to S2 was statistically significant in all groups (p<0.001). The NaOCl 2 degrees C group reported significantly less postoperative pain than the NaOCl 45 degrees C group (p<0.05). Postoperative analgesic intake was significantly higher in the NaOCl 45 degrees C group than in the NaOCl 2 degrees C group (p<0.05). Conclusion: We conclude that final irrigation with NaOCl at different temperatures results in similar antibacterial effectiveness. Final irrigation with cold NaOCl (2 degrees C) is better than NaOCl 45 degrees C when comparing postoperative pain levels.