Efficacy of intravenous magnesium sulfate infusion on postoperative pain and quality of recovery for septorhinoplasty: a randomized controlled study.


Kilic K., Sakat M. S., Sahin A., Ahiskalioglu E., Altunok H.

Acta oto-laryngologica, cilt.143, sa.11-12, ss.979-983, 2023 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 143 Sayı: 11-12
  • Basım Tarihi: 2023
  • Doi Numarası: 10.1080/00016489.2023.2289584
  • Dergi Adı: Acta oto-laryngologica
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier, International Bibliography of Social Sciences, Biotechnology Research Abstracts, CAB Abstracts, CINAHL, EMBASE, Linguistics & Language Behavior Abstracts, Veterinary Science Database
  • Sayfa Sayıları: ss.979-983
  • Atatürk Üniversitesi Adresli: Evet

Özet

Background: The pain that occurs after septorhinoplasty is an important factor affecting the comfort of the patient.Objectives: To investigate the effect of perioperative intravenous magnesium sulfate infusion on postoperative pain and quality of recovery in patients underwent septorhinoplasty surgery.Material and methods: One hundred twenty patients who underwent septorhinoplasty were randomly divided into two groups. Magnesium group received intravenous magnesium after induction of anesthesia (30 mg/kg), then infused until the end of the surgical procedure (9 mg/kg). The placebo group received the same volume of saline infusion. The VAS score was used for postoperative pain assessment, and the Quality of Recovery-40 (QoR-40) score was used for the assessment of recovery status.Results: The postoperative 30 min, 1st, 2nd, 4th (p < .001) and 24th hour (p < .05) VAS scores of the patients in the magnesium infusion group were significantly lower compared to the placebo group. Also; in terms of physical comfort (p < .001), emotional state (p < .05), psychological support, pain and total score values (p < .001), patients in magnesium group had significantly higher QoR-40 scores than those in placebo group.Conclusion: Intraoperative magnesium infusion, which is widely used in many surgeries to provide controlled hypotension, also contributes significantly to patient comfort with its positive effect on postoperative pain and recovery scores.