Palladium-catalyzed regioselective C2-arylation of 5-aminoindole

TAŞKESENLİGİL Y., LAFZİ F., KILIÇ H., SARAÇOĞLU N.

Journal of Heterocyclic Chemistry, cilt.56, sa.12, ss.3289-3296, 2019 (SCI-Expanded, Scopus) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 56 Sayı: 12
  • Basım Tarihi: 2019
  • Doi Numarası: 10.1002/jhet.3724
  • Dergi Adı: Journal of Heterocyclic Chemistry
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.3289-3296
  • Atatürk Üniversitesi Adresli: Evet

Özet

Pd(II)-catalyzed C-H arylations of 5-aminoindole using iodobenzenes as aryl source was studied. Despite pivalamide directing group at 5-position of the indole, the direct C2-arylation of the indole observed in high yields and with high regioselectivity.